Levobupivacaine

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Levobupivacaine base and levobupivacaine hydrochloride.

Editor—The British Journal of Anaesthesia has published six papers comparing the effects of levobupivacaine, the S(–)stereoisomer of bupivacaine with bupivacaine and ropivacaine, between 1998 and 2004, and three papers on various aspects of levobupivacaine alone. None of these papers calculated the concentration according to molarity. Two of them noted that there is a difference between the cli...

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Comparison of Levobupivacaine and Levobupivacaine with Dexmedetomidine in Infraumbilical Surgeries Under Spinal Anesthesia

Introduction Spinal anesthesia is a widely used technique providing faster onset with effective and uniformly distributed sensory and motor block. Due to decreased cardiovascular and central nervous system toxicity, levobupivacaine is a good alternative for spinal anesthesia. Dexmedetomidine when used intrathecally is associated with prolonged motor and sensory block, hemodynamic stability, and...

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Comparison of Intrathecal Levobupivacaine and Levobupivacaine plus Fentanyl for Cesarean Section

AIMS AND OBJECTIVES The aim of this study is to compare the effects of intrathecal levobupivacaine with levobupivacaine and fentanyl in patients undergoing cesarean section. METHODS Patients with American Society of Anesthesiologists Physical Status I and II scheduled for cesarean section under spinal anesthesia were randomly allocated with thirty patients each. Group L: levobupivacaine group...

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Update on local anesthetics: focus on levobupivacaine

In recent years levobupivacaine, the pure S (-)-enantiomer of bupivacaine, emerged as a safer alternative for regional anesthesia than its racemic parent. It demonstrated less affinity and strength of depressant effects onto myocardial and central nervous vital centers in pharmacodynamic studies, and a superior pharmacokinetic profile. Clinically, levobupivacaine is well tolerated in a variety ...

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Levobupivacaine for Regional Anesthesia and Pain Management

Levobupivacaine is an enantiomer of racemic bupivacaine with a safe pharmacological profile. We present a review of levobupivacaine and its current clinical use in regional anaesthesia and pain management. The pharmacokinetic and pharmacodynamic profile of levobupivacaine is discussed and a qualitative review of studies involving levobupivacaine for regional anaesthesia is presented. Comparison...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2001

ISSN: 0003-2409

DOI: 10.1046/j.1365-2044.2001.01964.x